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  5. ADVENTIST HEALTH SYSTEM/SUNBELT, INC.

ADVENTIST HEALTH SYSTEM/SUNBELT, INC. - Florida Company Profile

Headquarter

Company Details

Entity Name: ADVENTIST HEALTH SYSTEM/SUNBELT, INC.
Jurisdiction: FLORIDA
Filing Type: Domestic Non-Profit
Status: Active

The business entity is active. This status indicates that the business is currently operating and compliant with state regulations, suggesting a lower risk profile for lenders and potentially better creditworthiness.

Date Filed: 02 May 1973 (52 years ago)
Last Event: RESTATED ARTICLES
Event Date Filed: 11 May 2021 (4 years ago)
Document Number: 726307
FEI/EIN Number 591479658

Federal Employer Identification (FEI) Number assigned by the IRS.
Address: 900 HOPE WAY, ALTAMONTE SPRINGS, FL, 32714
Mail Address: 900 HOPE WAY, ALTAMONTE SPRINGS, FL, 32714
ZIP code: 32714
County: Seminole
Place of Formation: FLORIDA

Links between entities

Type:
Headquarter of
Company Number:
65d726b3-23f6-e311-ac2f-001ec94ffe7f
State:
MINNESOTA
URL:
View linked company profile
Type:
Headquarter of
Company Number:
0066834
State:
KENTUCKY
URL:
View linked company profile
Type:
Headquarter of
Company Number:
CORP_59388797
State:
ILLINOIS
URL:
View linked company profile

Key Officers & Management

Name Role Address
Shaw Terry President 900 HOPE WAY, ALTAMONTE SPRINGS, FL, 32714
ADDISCOTT LYNN Assistant Secretary 900 HOPE WAY, ALTAMONTE SPRINGS, FL, 32714
Werner Thomas L Director 1670 North Country Route 452, Eustis, FL, 32726
Didenko Dima Asst 14055 Riverdge Dr, Tampa, FL, 33637
Berrios Toni Secretary Adventist Health System, Altamonte Springs, FL, 32714
Saunders Michael Asst Adventist Health System, Altamonte Springs, FL, 32714
BROMME JEFF Agent 900 HOPE WAY, ALTAMONTE SPRINGS, FL, 32714

Unique Entity ID

A UEI is a government-provided number, like a tax ID number, that’s used to identify businesses eligible for federal grants, awards and contracts.

Note: In April 2022, the federal government replaced its old identifier of choice, the Data Universal Numbering System (DUNS) number, with a government-issued UEI. Now all the federal government’s Integrated Award Environment systems use UEI numbers instead of DUNS numbers. So any entity doing business with the federal government must register for a UEI.

Unique Entity ID:
LYYJFKCH2781
CAGE Code:
92FD3
UEI Expiration Date:
2025-07-16

Business Information

Activation Date:
2024-07-18
Initial Registration Date:
2021-06-02

National Provider Identifier

NPI Number:
1073301099
Certification Date:
2025-04-21
Link:
View on NPI website

Authorized Person:

Name:
SCOTT C BRADY
Role:
PRESIDENT/CEO
Phone:
4072002300

Taxonomy:

Selected Taxonomy:
363LF0000X - Family Nurse Practitioner
Is Primary:
No
Selected Taxonomy:
208000000X - Pediatrics Physician
Is Primary:
No
Selected Taxonomy:
363A00000X - Physician Assistant
Is Primary:
No
Selected Taxonomy:
207Q00000X - Family Medicine Physician
Is Primary:
Yes

Contacts:

Phone:
+1 407-200-2300
Phone:
+1 352-988-6160
Fax:
3529886161

Legal Entity Identifier

LEI Number:
549300UYHQRIS6O1T718

Registration Details:

Initial Registration Date:
2013-04-09
Next Renewal Date:
2019-09-18
Registration Status:
LAPSED
Validation Source:
FULLY_CORROBORATED

Fictitious Names

Registration Number Fictitious Name Status Filed Date Expiration Date Cancellation Date Mailing Address
G25000070117 ADVENTHEALTH PRIMARY CARE+ TAVARES ACTIVE 2025-05-29 2030-12-31 - 1418 E BURLEIGH BLVD, TAVARES, FL, 32778
G25000070118 ADVENTHEALTH CENTRA CARE TAVARES ACTIVE 2025-05-29 2030-12-31 - 1420 E BURLEIGH BLVD, TAVARES, FL, 32778
G25000067595 ADVENTHEALTH CENTRA CARE SOUTHERN TRACE ACTIVE 2025-05-22 2030-12-31 - 3310 WEDGEWOOD LANE, THE VILLAGES, FL, 32162
G25000065992 ADVENTHEALTH INTENSIVE CARDIAC REHAB SEBRING ACTIVE 2025-05-19 2030-12-31 - 4200 SUN N LAKE BLVD, 1ST FLOOR, SEBRING, FL, 33872
G25000059443 ADVENTHEALTH SPORTS MED & REHAB WINTER PARK VILLAGE ACTIVE 2025-05-02 2030-12-31 - 351 N ORLANDO AVE, WINTER PARK, FL, 32789
G25000056720 ADVENTHEALTH EDEN BOUTIQUE WINTER PARK ACTIVE 2025-04-28 2030-12-31 - 2100 GLENWOOD DRIVE, SUITE 104, WINTER PARK, FL, 32792
G25000054740 ADVENTHEALTH PRIMARY CARE+ HAINES CITY ACTIVE 2025-04-23 2030-12-31 - 35726 US HIGHWAY 27, HAINES CITY, FL, 33844
G25000054069 ADVENTHEALTH CENTRA CARE HAINES CITY ACTIVE 2025-04-22 2030-12-31 - 35716 US HIGHWAY 27, HAINES CITY, FL, 33844
G25000040229 ADVENTHEALTH CENTRA CARE HUNT CLUB ACTIVE 2025-03-21 2030-12-31 - 2715 E SEMORAN BLVD, APOPKA, FL, 32703
G25000040227 ADVENTHEALTH CENTRA CARE CLERMONT HAMMOCK RIDGE ACTIVE 2025-03-21 2030-12-31 - 3380 SOUTH US HIGHWAY 27, CLERMONT, FL, 34711

Events

Event Type Filed Date Value Description
RESTATED ARTICLES 2021-05-11 - -
RESTATED ARTICLES 2015-10-06 - -
MERGER 2011-12-30 - CORPORATION WAS A MERGER RESULT. TOTAL NUMBER OF QUALIFIED CORPORATION(S) INVOLVED WAS 0. MERGER NUMBER 300000119143
REGISTERED AGENT NAME CHANGED 2011-12-16 BROMME, JEFF -
REGISTERED AGENT ADDRESS CHANGED 2011-12-16 900 HOPE WAY, ALTAMONTE SPRINGS, FL 32714 -
CHANGE OF PRINCIPAL ADDRESS 2011-12-15 900 HOPE WAY, ALTAMONTE SPRINGS, FL 32714 -
CHANGE OF MAILING ADDRESS 2011-12-15 900 HOPE WAY, ALTAMONTE SPRINGS, FL 32714 -
MERGER 2009-06-30 - CORPORATION WAS A MERGER RESULT. TOTAL NUMBER OF QUALIFIED CORPORATION(S) INVOLVED WAS 1. MERGER NUMBER 500000097855
MERGER 2009-03-19 - CORPORATION WAS A MERGER RESULT. TOTAL NUMBER OF QUALIFIED CORPORATION(S) INVOLVED WAS 0. MERGER NUMBER 900000095049
MERGER 2006-12-29 - CORPORATION WAS A MERGER RESULT. TOTAL NUMBER OF QUALIFIED CORPORATION(S) INVOLVED WAS 0. MERGER NUMBER 300000062043

Debts

Document Number Status Case Number Name of Court Date of Entry Expiration Date Amount Due Plaintiff
J11000151022 LAPSED 09-225-CCS 10TH JUDICIAL, HIGHLANDS CO 2011-02-17 2016-03-14 $8,247.61 ADVENTIST HEALTH SYSTEM/SUNBELT, INC., D/B/AFLORIDA HOSPITAL HEARTLAND DIVISION, 4200 SUN N LAKE BOULEVARD, SEBRING, FLORIDA 3370
J02000144679 LAPSED SCO-02-944 ORANGE COUNTY COURT 2002-03-27 2007-04-12 $2734.29 INVENSYS BUILDING SYSTEMS, INC., 7101 PRESIDENTS DRIVE, #250, ORLANDO, FL 32809

Court Cases

Title Case Number Docket Date Status
BARBARA A. BOURQUE, AS GUARDIAN ADVOCATE OF JANE DOE, Appellant v. ADVENTIST HEALTH SYSTEM/SUNBELT, INC., Appellee. 6D2024-2815 2025-01-05 Open
Classification NOA Final - Circuit Civil - Other
Court 6th District Court of Appeal
Originating Court Circuit Court for the Ninth Judicial Circuit, Orange County
2015-CA-000716 AND 2017-CA-007555

Parties
Name BARBARA A. BOURQUE
Role Appellant
Status Active
Representations Steven Gerald Mason, Eric Harald Faddis
Name ADVENTIST HEALTH SYSTEM/SUNBELT, INC.
Role Appellee
Status Active
Representations James Brent Allen, Ashley Martell Fromm, Brooke Taylor Jost, Elisabeth Avilla Adamson, Gavrila A. Alexa Brotz
Name Orange Clerk
Role Lower Tribunal Clerk
Status Active

Docket Entries
Docket Date 2025-01-06
Type Order
Subtype Order on Filing Fee
Description This appeal has been filed without the filing fee required under section 35.22(2)(a), Florida Statutes. Within twenty days of this order, Appellant shall forward the required $300.00 filing fee or, if applicable, an order or certificate from the lower tribunal finding Appellant indigent. Failure to comply with this order will result in the dismissal of this case.
View View File
Docket Date 2025-01-06
Type Letter
Subtype Acknowledgment Letter
Description Acknowledgment Letter
View View File
Docket Date 2025-01-05
Type Notice
Subtype Notice of Appeal
Description Notice of Appeal
On Behalf Of BARBARA A. BOURQUE
View View File
Adventist Health System/Sunbelt, Inc. d/b/a Florida Hospital Altamonte, Petitioner(s), v. Todd Copeland, Esquire, as Guardian ad Litem to O.L., a Minor, and Jessica Light and Raymond Light, Individually, and on behalf of O.L., a Minor, Florida Hospital Medical Group d/b/a Neonatal Care Center, Florida Hospital Medical Group d/b/a Florida Women's Center, and Sheila Ramos-Martinez, Respondent(s). 5D2024-3332 2024-12-04 Open
Classification Original Proceedings - Circuit Civil - Certiorari
Court 5th District Court of Appeal
Originating Court Circuit Court for the Eighteenth Judicial Circuit, Seminole County
2016-CA-000487

Parties
Name ADVENTIST HEALTH SYSTEM/SUNBELT, INC.
Role Petitioner
Status Active
Representations Dinah Stein, Philip Manuel Berberian, Travase Lloyd Erickson
Name Florida Hospital Altamonte
Role Petitioner
Status Active
Name Florida Hospital Medical Group d/b/a Neonatal Care Center
Role Petitioner
Status Active
Representations John William Bocchino
Name Florida Hospital Medical Group d/b/a Florida Women's Center
Role Petitioner
Status Active
Representations Clayton M. Williams, Michael Allen Estes, Christian Trowbridge
Name Sheila Ramos-Martinez
Role Petitioner
Status Active
Representations Wilbert Rhulx Vancol, Rafael Eduardo Martinez
Name Jessica Light
Role Respondent
Status Active
Representations Carlos Raul Diez-Arguelles, Maria Dolores Tejedor
Name Raymond Light
Role Respondent
Status Active
Name O.L., A Minor
Role Respondent
Status Active
Name Todd Eugene Copeland
Role Respondent
Status Active
Name Hon. Susan Weindorf Stacy
Role Judge/Judicial Officer
Status Active

Docket Entries
Docket Date 2024-12-20
Type Order
Subtype Order on Motion for Extension of Time to File Response
Description Order on Motion for Extension of Time to File Response TO 1/27/25
View View File
Docket Date 2024-12-19
Type Motions Extensions
Subtype Motion for Extension of Time to File Response
Description Motion for Extension of Time to File Response FOR RS, JESSICA LIGHT AND RAYMOND LIGHT
On Behalf Of Jessica Light
Docket Date 2024-12-18
Type Order
Subtype Order on Motion to Consolidate
Description Order on Motion to Consolidate; J. LIGHT AND R. LIGHT MOT CONDOLIDATE DENIED; CASE NUMBERS 5D2024-3304, 5D2024-3332 & 5D2024-3336 TRAVEL TOGETHER; ASSIGNED TO SAME PANEL FOR CONSIDERATION
View View File
Docket Date 2024-12-10
Type Motions Other
Subtype Motion To Consolidate
Description Motion To Consolidate
On Behalf Of Jessica Light
Docket Date 2024-12-05
Type Order
Subtype Order to File Response
Description Order to File Response; RESPONSE W/IN 20 DYS; REPLY W/IN 10 DYS
View View File
Docket Date 2024-12-04
Type Event
Subtype Fee Paid in Full - $300
Description Fee Paid in Full - $300
View View File
Docket Date 2024-12-04
Type Order
Subtype Order on Filing Fee
Description Order on Filing Fee - Fee Paid
View View File
Docket Date 2024-12-04
Type Letter
Subtype Acknowledgment Letter
Description Acknowledgment Letter
View View File
Docket Date 2024-12-04
Type Record
Subtype Appendix
Description Appendix to Petition
Docket Date 2024-12-04
Type Petition
Subtype Petition Certiorari
Description Petition Certiorari - Filed Here 12/3/2024
On Behalf Of Adventist Health System/Sunbelt, Inc.
BARBARA A. BORQUE, AS GUARDIAN FOR ASHLEY KARLEN (WARD), Petitioners v. ADVENTIST HEALTH SYSTEM/SUNBELT, INC., THOMAS D. RIVERS, TINA M. YAUS, HOLLIE GENELL LEBRON, VICKIE A. SCOTT, WENDY A. JONES, ROBERT S. BATEMAN, FRANK QUINTERO, JR., JOSE M. CARRASQUILLO, NATHAN R. WILSON, CHRISTOPHER C. FENDER, AFTAB QADIR, M.D., and KELLY DAVIS SHUTTERA, Respondents. 6D2024-2435 2024-11-15 Closed
Classification Original Proceedings - Circuit Civil - Mandamus
Court 6th District Court of Appeal
Originating Court Circuit Court for the Ninth Judicial Circuit, Orange County
2015-CA-000716 and 2017-CA-007555

Parties
Name BARBARA A. BORQUE
Role Petitioner
Status Active
Representations Steven Gerald Mason, Eric Harald Faddis
Name ASHLEY KARLEN
Role Petitioner
Status Active
Representations Steven Gerald Mason, Eric Harald Faddis
Name THOMAS D. RIVERS
Role Respondent
Status Active
Representations James Brent Allen, Ashley Martell Fromm, Brooke Taylor Jost, Elisabeth Avilla Adamson, Gavrila A. Alexa Brotz
Name TINA M. YAUS
Role Respondent
Status Active
Representations James Brent Allen, Ashley Martell Fromm, Brooke Taylor Jost, Elisabeth Avilla Adamson, Gavrila A. Alexa Brotz
Name HOLLIE GENELL LEBRON
Role Respondent
Status Active
Representations James Brent Allen, Ashley Martell Fromm, Brooke Taylor Jost, Elisabeth Avilla Adamson, Gavrila A. Alexa Brotz
Name VICKIE A. SCOTT
Role Respondent
Status Active
Representations James Brent Allen, Ashley Martell Fromm, Brooke Taylor Jost, Elisabeth Avilla Adamson, Gavrila A. Alexa Brotz
Name WENDY A. JONES
Role Respondent
Status Active
Representations James Brent Allen, Ashley Martell Fromm, Brooke Taylor Jost, Elisabeth Avilla Adamson, Gavrila A. Alexa Brotz
Name ROBERT S. BATEMAN
Role Respondent
Status Active
Representations James Brent Allen, Ashley Martell Fromm, Brooke Taylor Jost, Elisabeth Avilla Adamson, Gavrila A. Alexa Brotz
Name FRANK QUINTERO, JR.
Role Respondent
Status Active
Representations James Brent Allen, Ashley Martell Fromm, Brooke Taylor Jost, Elisabeth Avilla Adamson, Gavrila A. Alexa Brotz
Name JOSE M. CARRASQUILLO
Role Respondent
Status Active
Representations James Brent Allen, Ashley Martell Fromm, Brooke Taylor Jost, Elisabeth Avilla Adamson, Gavrila A. Alexa Brotz
Name NATHAN R. WILSON LLC
Role Respondent
Status Active
Representations James Brent Allen, Ashley Martell Fromm, Brooke Taylor Jost, Elisabeth Avilla Adamson, Gavrila A. Alexa Brotz
Name AFTAB QADIR, M.D.
Role Respondent
Status Active
Representations James Brent Allen, Ashley Martell Fromm, Brooke Taylor Jost, Elisabeth Avilla Adamson, Gavrila A. Alexa Brotz
Name KELLY DAVIS SHUTTERA
Role Respondent
Status Active
Representations James Brent Allen, Ashley Martell Fromm, Brooke Taylor Jost, Elisabeth Avilla Adamson, Gavrila A. Alexa Brotz
Name Hon. Eric J. Netcher
Role Judge/Judicial Officer
Status Active
Name Orange Clerk
Role Lower Tribunal Clerk
Status Active
Name ADVENTIST HEALTH SYSTEM/SUNBELT, INC.
Role Respondent
Status Active
Representations James Brent Allen, Ashley Martell Fromm, Brooke Taylor Jost, Elisabeth Avilla Adamson, Gavrila A. Alexa Brotz
Name CHRISTOPHER C. FENDER
Role Respondent
Status Active
Representations James Brent Allen, Ashley Martell Fromm, Brooke Taylor Jost, Elisabeth Avilla Adamson, Gavrila A. Alexa Brotz

Docket Entries
Docket Date 2024-11-18
Type Event
Subtype Fee Satisfied
Description Fee Satisfied
Docket Date 2024-11-18
Type Miscellaneous Document
Subtype Pay Case Filing Fee-300
Description Pay Case Filing Fee-300
On Behalf Of BARBARA A. BORQUE
Docket Date 2024-11-18
Type Notice
Subtype Notice of Related Case or Issue
Description Notice of Related Case or Issue
On Behalf Of BARBARA A. BORQUE
Docket Date 2024-11-15
Type Notice
Subtype Notice
Description NOTICE OF COMPLIANCE OF FILING FEE ORDER OF NOVEMBER 15, 2024
On Behalf Of BARBARA A. BORQUE
Docket Date 2024-11-15
Type Order
Subtype Order on Filing Fee
Description This petition has been filed without the filing fee required under section 35.22(2)(a), Florida Statutes. Within twenty days of this order, Petitioner shall forward the required $300.00 filing fee or, if applicable, a motion to proceed in forma pauperis with an affidavit of indigency. A form motion for this purpose may be found on this Court's website at https://6dca.flcourts.gov/Clerk-s-Office/Forms, and a copy of this form motion is enclosed with this order if served by mail. Failure to comply with this order will result in the dismissal of this case.
Docket Date 2024-11-15
Type Letter
Subtype Acknowledgment Letter
Description Acknowledgment Letter
Docket Date 2024-11-15
Type Misc. Events
Subtype Order Appealed
Description Order Appealed
Docket Date 2024-11-15
Type Petition
Subtype Petition Mandamus
Description Petition Mandamus
On Behalf Of BARBARA A. BORQUE
Docket Date 2024-12-30
Type Mandate
Subtype Mandate
Description Mandate
View View File
Docket Date 2024-12-13
Type Disposition by Order
Subtype Dismissed
Description Petitioner's petition for writ of mandamus, dated November 15, 2024, is dismissed without prejudice as premature. If Petitioner's reasonable efforts to seek entry of a final judgment from the trial court in the next thirty days are unsuccessful, Petitioner may file an appropriate new petition.
View View File
JAMES SMITH KARLAN, Petitioner, ADVENTIST HEALTH SYSTEM/SUNBELT, INC., THOMAS D. RIVERS, TINA M. YAUS, HOLLIE GENELL LEBRON, VICKIE A. SCOTT, KELLY DAVIS SHUTTERA, WENDY A. JONES, ROBERT S. BATEMAN, FRANK QUINTERO, JR., JOSE M. CARRASQUILLO, NATHAN R. WILSON, CHRISTOPHER C. FENDER, and AFTAB QADIR, M.D., Respondent(s). 6D2024-1412 2024-07-16 Closed
Classification Original Proceedings - Circuit Civil - Mandamus
Court 6th District Court of Appeal
Originating Court Circuit Court for the Ninth Judicial Circuit, Orange County
2015-CA-000716

Circuit Court for the Ninth Judicial Circuit, Orange County
2017-CA-007555-O

Parties
Name JAMES SMITH KARLAN
Role Petitioner
Status Active
Representations Steven Mason, Eric Harald Faddis
Name TINA M. YAUS
Role Respondent
Status Active
Representations Eric Rolland Eide, Philip Wallace
Name HOLLIE GENELL LEBRON
Role Respondent
Status Active
Representations Eric Rolland Eide, Philip Wallace
Name VICKIE A. SCOTT
Role Respondent
Status Active
Representations Eric Rolland Eide, Philip Wallace
Name KELLY DAVIS SHUTTERA
Role Respondent
Status Active
Representations Eric Rolland Eide, Philip Wallace
Name WENDY A. JONES
Role Respondent
Status Active
Representations Eric Rolland Eide, Philip Wallace
Name ROBERT S. BATEMAN
Role Respondent
Status Active
Representations Eric Rolland Eide, Philip Wallace
Name FRANK QUINTERO, JR.
Role Respondent
Status Active
Representations Eric Rolland Eide, Philip Wallace
Name JOSE M. CARRASQUILLO
Role Respondent
Status Active
Representations Eric Rolland Eide, Philip Wallace
Name NATHAN R. WILSON LLC
Role Respondent
Status Active
Representations Eric Rolland Eide, Philip Wallace
Name CHRISTOPHER C. FENDER
Role Respondent
Status Active
Representations Eric Rolland Eide, Philip Wallace
Name AFTAB QADIR, M.D.
Role Respondent
Status Active
Representations Eric Rolland Eide, Philip Wallace
Name Hon. Eric J. Netcher
Role Judge/Judicial Officer
Status Active
Name Hon. Patricia L. Strowbridge
Role Judge/Judicial Officer
Status Active
Name Hon. Kevin Brett Weiss
Role Judge/Judicial Officer
Status Active
Name Orange Clerk
Role Lower Tribunal Clerk
Status Active
Name ADVENTIST HEALTH SYSTEM/SUNBELT, INC.
Role Respondent
Status Active
Representations Eric Rolland Eide, Philip Wallace
Name THOMAS D. RIVERS
Role Respondent
Status Active
Representations Eric Rolland Eide, Philip Wallace

Docket Entries
Docket Date 2024-07-16
Type Letter
Subtype Acknowledgment Letter
Description Acknowledgment Letter
Docket Date 2024-07-16
Type Petition
Subtype Petition Mandamus
Description Petition Mandamus
Docket Date 2024-09-05
Type Disposition by Order
Subtype Denied
Description This petition for writ of mandamus is denied as moot.
View View File
Docket Date 2024-08-21
Type Misc. Events
Subtype Status Report
Description MISS KARLEN'S SECOND STATUS REPORT AND REQUEST FOR AN ORDER OF DISMISSAL WITHOUT PREJUDICE
On Behalf Of JAMES SMITH KARLAN
Docket Date 2024-08-06
Type Misc. Events
Subtype Status Report
Description MISS KARLEN'S ADDENDUM/STATUS REPORT TO COURT ON PETITION FORR WRIT OF MANDAMUS
On Behalf Of JAMES SMITH KARLAN
Docket Date 2024-07-17
Type Miscellaneous Document
Subtype Pay Case Filing Fee-300
Description Pay Case Filing Fee-300
On Behalf Of JAMES SMITH KARLAN
View View File
Docket Date 2024-07-17
Type Event
Subtype Fee Satisfied
Description Fee Satisfied
Docket Date 2024-07-16
Type Order
Subtype Order on Filing Fee
Description This petition has been filed without the filing fee required under section 35.22(2)(a), Florida Statutes. Within forty days of this order, Petitioner shall forward the required $300.00 filing fee or, if applicable, a motion to proceed in forma pauperis with a supporting affidavit of indigency. Failure to comply with this order may result in the dismissal of this petition without further notice.
Docket Date 2025-01-03
Type Mandate
Subtype Mandate
Description Mandate
View View File
HEALTH FIRST, INC., D/B/A HEALTH FIRST HOLMES REGIONAL MEDICAL CENTER, HOLMES REGIONAL MEDICAL CENTER, INC., D/B/A HEALTH FIRST HOLMES REGIONAL MEDICAL CENTER, Petitioner(s) v. LATOYA DAWKINS AND DAVID DAWKINS, INDIVIDUALLY, AND AS THE NATURAL PARENTS ON BEHALF OF D. W., A MINOR, ET AL Respondent(s). 6D2024-1215 2024-06-13 Closed
Classification Original Proceedings - Circuit Civil - Certiorari
Court 6th District Court of Appeal
Originating Court Circuit Court for the Ninth Judicial Circuit, Orange County
2023-CA-005957-O

Parties
Name HEALTH FIRST, INC., D/B/A HEALTH FIRST HOLMES REGIONAL MEDICAL CENTER
Role Petitioner
Status Active
Representations Jessica Hernandez, Scott Edward Solomon, Gabriel Lopez, Karen Montas
Name HOLMES REGIONAL MEDICAL CENTER, INC., D/B/A HEALTH FIRST HOLMES REGIONAL MEDICAL CENTER
Role Petitioner
Status Active
Representations Jessica Hernandez, Scott Edward Solomon, Gabriel Lopez, Karen Montas
Name LATOYA DAWKINS
Role Respondent
Status Active
Representations Jordan Andrew Dulcie, Andrew A. Harris, Grace Streicher
Name DAVID DAWKINS
Role Respondent
Status Active
Representations Jordan Andrew Dulcie, Andrew A. Harris, Grace Streicher
Name D. D., A MINOR
Role Respondent
Status Active
Representations Jordan Andrew Dulcie, Andrew A. Harris, Grace Streicher
Name EDWIN BRUCE HAYES, M.D.
Role Respondent
Status Active
Representations Joseph Charles Ingram
Name OB/GYN SPECIALISTS OF BREVARD, LLC
Role Respondent
Status Active
Representations Joseph Charles Ingram
Name FLORIDA HOSPITAL MEDICAL GROUP, INC., D/B/A ADVENT HEALTH MEDICAL GROUP OB GYN
Role Respondent
Status Active
Representations Joseph Charles Ingram
Name ADVENTIST HEALTH SYSTEM/SUNBELT, INC.
Role Respondent
Status Active
Representations Joseph Charles Ingram
Name Orange Clerk
Role Lower Tribunal Clerk
Status Active
Name Hon. Vincent Falcone, III
Role Judge/Judicial Officer
Status Active

Docket Entries
Docket Date 2024-11-05
Type Response
Subtype Reply
Description REPLY TO RESPONSE TO PETITION FOR WRIT OF CERTIORARI
On Behalf Of HEALTH FIRST, INC., D/B/A HEALTH FIRST HOLMES REGIONAL MEDICAL CENTER
Docket Date 2024-10-25
Type Order
Subtype Order on Motion for Extension of Time to File Response
Description Respondent's unopposed motion for extension of time to respond is denied as moot. Respondent's response is accepted as filed.
View View File
Docket Date 2024-10-24
Type Motions Relating to Attorney Fees/Costs
Subtype Motion For Attorney's Fees
Description RESPONDENTS' MOTION FOR APPELLATE ATTORNEYS' FEES
On Behalf Of DAVID DAWKINS
Docket Date 2024-10-18
Type Response
Subtype Response
Description RESPONDENT'S RESPONSE TO PETITION FOR WRIT OF CERTIORARI
On Behalf Of LATOYA DAWKINS
Docket Date 2024-10-15
Type Motions Extensions
Subtype Motion for Extension of Time to File Response
Description RESPONDENT'S UNOPPOSED MOTION FOR EXTENSION OF TIME TO FILE RESPONSE TO PETITION FOR WRIT OF CERTIORARI
On Behalf Of LATOYA DAWKINS
Docket Date 2024-10-08
Type Notice
Subtype Notice of Appearance
Description Notice of Appearance
On Behalf Of LATOYA DAWKINS
Docket Date 2024-09-09
Type Order
Subtype Order to File Response
Description Respondents shall serve a response to the petition for writ of certiorari within 30 days. Petitioners may serve a reply within 30 days thereafter. The parties shall keep this court apprised of all hearings or trial dates that may affect this proceeding.
View View File
Docket Date 2024-06-20
Type Miscellaneous Document
Subtype Pay Case Filing Fee-300
Description Pay Case Filing Fee-300
On Behalf Of HEALTH FIRST, INC., D/B/A HEALTH FIRST HOLMES REGIONAL MEDICAL CENTER
View View File
Docket Date 2024-06-20
Type Event
Subtype Fee Satisfied
Description Fee Satisfied
Docket Date 2024-06-14
Type Notice
Subtype Notice
Description NOTICE OF INCLUSION IN E-SERVICE LIST
On Behalf Of HEALTH FIRST, INC., D/B/A HEALTH FIRST HOLMES REGIONAL MEDICAL CENTER
Docket Date 2024-06-13
Type Letter
Subtype Acknowledgment Letter
Description Acknowledgment Letter
View View File
Docket Date 2024-06-13
Type Record
Subtype Appendix
Description Appendix
On Behalf Of HEALTH FIRST, INC., D/B/A HEALTH FIRST HOLMES REGIONAL MEDICAL CENTER
View View File
Docket Date 2024-06-13
Type Petition
Subtype Petition All Writs
Description Petition All Writs
On Behalf Of HEALTH FIRST, INC., D/B/A HEALTH FIRST HOLMES REGIONAL MEDICAL CENTER
View View File
Docket Date 2025-01-07
Type Mandate
Subtype Mandate
Description Mandate
View View File
Docket Date 2024-12-19
Type Order
Subtype Order on Motion For Attorney's Fees
Description ORDERED that Respondents' Motion For Attorney's Fees, filed on October 23, 2024, is provisionally granted upon the lower court's determination, at the conclusion of the case and pursuant to Florida Rule of Civil Procedure 1.442, that Appellee is entitled to attorney's fees pursuant to the proposal for settlement.
View View File
Docket Date 2024-12-19
Type Disposition by Order
Subtype Denied
Description The Petition for Writ of Certiorari is denied.
View View File
Docket Date 2024-06-13
Type Order
Subtype Order on Filing Fee
Description This petition has been filed without a filing fee required by section 35.22(2)(a), Florida Statutes. Within twenty days, Counsel for petitioner shall forward the required $300.00 filing fee or, if applicable, an affidavit of insolvency in conformity with the requirements of chapter 57, Florida Statutes, to this court. If this court does not receive either of the above within the prescribed time, this petition may be subject to dismissal without further notice."
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Documents

Name Date
AMENDED ANNUAL REPORT 2025-01-20
ANNUAL REPORT 2025-01-02
AMENDED ANNUAL REPORT 2024-09-30
ANNUAL REPORT 2024-02-29
ANNUAL REPORT 2023-01-10
AMENDED ANNUAL REPORT 2022-06-14
AMENDED ANNUAL REPORT 2022-01-06
ANNUAL REPORT 2022-01-05
Restated Articles 2021-05-11
AMENDED ANNUAL REPORT 2021-04-20

USAspending Awards / Contracts

Procurement Instrument Identifier:
DJBSERMV2020082
Link:
View Award on USAspending website
Award Or Idv Flag:
AWARD
Award Type:
PO
Action Obligation:
3001.96
Base And Exercised Options Value:
3001.96
Base And All Options Value:
3001.96
Awarding Agency Name:
Department of Justice
Performance Start Date:
2013-09-24
Description:
IGF::CT,CL::IGF NON-BOP MEDICAL
Naics Code:
622110: GENERAL MEDICAL AND SURGICAL HOSPITALS
Product Or Service Code:
Q523: MEDICAL- SURGERY
Procurement Instrument Identifier:
DJBSERMV2020079
Link:
View Award on USAspending website
Award Or Idv Flag:
AWARD
Award Type:
PO
Action Obligation:
29734.00
Base And Exercised Options Value:
29734.00
Base And All Options Value:
29734.00
Awarding Agency Name:
Department of Justice
Performance Start Date:
2013-09-24
Description:
IGF::CT,CL::IGF NON-BOP MEDICAL
Naics Code:
622110: GENERAL MEDICAL AND SURGICAL HOSPITALS
Product Or Service Code:
Q523: MEDICAL- SURGERY
Procurement Instrument Identifier:
DJBSERMV2020033
Link:
View Award on USAspending website
Award Or Idv Flag:
AWARD
Award Type:
PO
Action Obligation:
9993.00
Base And Exercised Options Value:
9993.00
Base And All Options Value:
9993.00
Awarding Agency Name:
Department of Justice
Performance Start Date:
2013-06-24
Description:
IGF::CT,CL::IGF NON-BOP MEDICAL
Naics Code:
622110: GENERAL MEDICAL AND SURGICAL HOSPITALS
Product Or Service Code:
Q523: MEDICAL- SURGERY

USAspending Awards / Financial Assistance

Date:
2024-07-16
Link:
View on USAspending
Awarding Agency Name:
Department of Health and Human Services
Transaction Description:
DEFINING THE QUANTITATIVE FUNCTIONAL MECHANISMS THAT UNDERLY GUT MICROBIOME-DIET INTERACTIONS CONTRIBUTING TO HUMAN ENERGY BALANCE - PROJECT SUMMARY THE OBESITY EPIDEMIC CONTINUES TO AFFLICT POPULATIONS GLOBALLY. THE LITERATURE IS REPLETE WITH OBSERVATIONAL STUDIES PURPORTING A ROLE OF THE GUT MICROBIOME IN BODY WEIGHT REGULATION. THE MAIN GAP IN THE DEVELOPMENT OF MICROBIOME-TARGETED THERAPEUTICS TO TREAT OBESITY IS A DEEP UNDERSTANDING OF THE CAUSAL MECHANISMS BY WHICH MICROBES IMPACT ENERGY BALANCE IN HUMANS. IN A FIRST OF ITS KIND STUDY, WE IMPLEMENTED A QUANTITATIVE BIOENERGETICS PARADIGM IN WHICH HUMAN ENERGY BALANCE WAS DEEPLY AND PRECISELY PHENOTYPED (ENERGY INTAKE, EXPENDITURE AND FECAL ENERGY LOSS) DURING AN INPATIENT RANDOMIZED CONTROLLED CROSSOVER FEEDING STUDY. WE USED DIETS THAT DELIVERED MINIMAL (WESTERN DIET; WD) VERSUS HIGH (MICROBIOME ENHANCER DIET; MBD) AMOUNTS OF MICROBIOTA FERMENTABLE DIETARY SUBSTRATES TO THE COLON TO REPROGRAM THE GUT MICROBIOME WITHIN INDIVIDUALS. WE UNCOVERED DIET-HOST-MICROBE INTERACTIONS THAT IMPACTED HUMAN ENERGY BALANCE VIA INCREASED FECAL ENERGY LOSS AND THUS, LOWER METABOLIZABLE ENERGY (ME) THAT WAS DUE IN PART TO AN INCREASE IN MICROBIAL BIOMASS ON THE MBD AS COMPARED TO THE WD. TO ADVANCE THIS WORK, WE NEED TO UNDERSTAND THE QUANTITATIVE AND FUNCTIONAL MECHANISMS BY WHICH THE GUT MICROBIOME IMPACTS ME WHEN EXPOSED TO DIFFERENT DIETS. WE PROPOSE TWO AIMS TO ACCOMPLISH THIS. IN AIM 1A, WE WILL DETERMINE THE AMOUNT OF FECAL ENERGY LOSS THAT IS DUE TO SHUNTING OF ENERGY FROM THE HUMAN DIET TOWARDS BIOMASS EXPANSION (AND THUS AWAY FROM THE HOST) TO TEST THE HYPOTHESIS THAT THE DIETARY ENERGY DIVERTED FROM HOST TOWARDS BIOMASS EXPANSION IS LARGE ENOUGH TO PROMOTE LOWER ME (NET NEGATIVE ENERGY BALANCE) ON THE MBD VS. THE WD. IN AIM 1B, WE WILL PERFORM ABSOLUTE QUANTIFICATION OF MICROBIAL SPECIES TO DETERMINE WHICH ONES ARE THE DOMINANT PLAYERS IN BIOMASS EXPANSION AND THEIR PROPORTIONAL CONTRIBUTION TO FECAL BIOMASS ENERGY. IN AIM 2A, WE WILL IMPLEMENT A NOVEL INTEGRATED MULTI-OMICS WORKFLOW AIMED AT DETERMINING MICROBIAL FUNCTIONS AND SUBSTRATE PREFERENCES IN VIVO. THESE DATA WILL TELL US WHAT THE MICROBES “EAT”, WHICH SPECIFIC SPECIES COMPETE FOR THE SAME DIETARY SUBSTRATES, AND THE ASSOCIATED FUNCTIONS OF THE MICROBIAL COMMUNITY WHEN SPECIFIC DIETARY SUBSTRATES ARE AVAILABLE. THESE DATA WILL BE VALIDATED IN AIM 2B BY PERFORMING EX VIVO EXPERIMENTS TO CHANGE THE ABSOLUTE ABUNDANCE OF SPECIFIC MICROBES THAT CONTRIBUTE MOST TO BIOMASS BY ADDITION OF THE PREFERRED SUBSTRATES OF THOSE MICROBES. THE OVERALL OUTCOME OF THIS PROJECT IS THAT WE WILL HAVE AN UNPRECEDENTED UNDERSTANDING OF THE QUANTITATIVE MICROBIAL MECHANISMS THAT DRIVE HUMAN ENERGY BALANCE.
Obligated Amount:
1248398.00
Face Value Of Loan:
0.00
Total Face Value Of Loan:
0.00
Date:
2024-06-12
Link:
View on USAspending
Awarding Agency Name:
Department of Health and Human Services
Transaction Description:
EXERCISE, STRESS BIOMARKERS, AND ALZHEIMER'S DISEASE NEUROPATHOLOGY - ABSTRACT AEROBIC EXERCISE MIGHT AFFECT THE BRAIN THROUGH A PLURALITY OF PATHWAYS, INCLUDING VIA MODULATION OF THE HYPOTHALAMIC-PITUITARY-ADRENAL (HPA) AXIS. THE HPA AXIS REGULATES THE RELEASE OF CORTISOL, A GLUCOCORTICOID HORMONE THAT IS RELATED TO IMPAIRED COGNITIVE PERFORMANCE, REDUCED BRAIN VOLUME AND FUNCTION, AND INCREASED RISK FOR ALZHEIMER’S DISEASE (AD), INCLUDING MARKERS OF AD PATHOPHYSIOLOGY. MANY OF THE SAME BRAIN REGIONS AND COGNITIVE DOMAINS AFFECTED BY HIGH CORTISOL LEVELS ARE THE SAME THAT ARE POSITIVELY AFFECTED BY ENGAGING IN REGULAR AEROBIC EXERCISE. THUS, WE HYPOTHESIZE THAT AEROBIC EXERCISE-INDUCED CHANGES IN CORTISOL MIGHT ACT AS A PATHWAY BY WHICH LONG-TERM EXERCISE INFLUENCES NEUROCOGNITIVE HEALTH. FURTHER, WE SPECULATE THAT AEROBIC EXERCISE MIGHT INFLUENCE AD NEUROPATHOLOGY THROUGH ITS INFLUENCE ON CORTISOL. ADDRESSING THESE GAPS COULD HAVE FAR-REACHING APPLICATION FOR ADOPTING EXERCISE AS A METHOD OF PREVENTING OR TREATING COGNITIVE IMPAIRMENT. WE ADDRESS THESE UNANSWERED QUESTIONS IN THIS HIGH-RISK/HIGH-REWARD R21 APPLICATION. THE PROPOSED STUDY WILL CONDUCT AN ANALYSIS OF HAIR CORTISOL CONCENTRATION (HCC) IN A LARGE AND UNIQUELY WELL-CHARACTERIZED SAMPLE OF COGNITIVELY NORMAL OLDER ADULTS (N=648). HAIR SAMPLES HAVE BEEN COLLECTED AND BANKED BOTH BEFORE AND AFTER A MULTI-SITE PHASE III DOSE-RESPONSE 12-MONTH SUPERVISED RANDOMIZED CLINICAL TRIAL OF EXERCISE TITLED INVESTIGATING GAINS IN NEUROCOGNITION IN AN INTERVENTION TRIAL OF EXERCISE (IGNITE). THE IGNITE STUDY AND THE BANKED HAIR SAMPLES IN N=648 WILL SERVE AS THE BASIS FOR THE PROPOSED STUDY. THIS PROPOSAL REFLECTS AN UNPRECEDENTED OPPORTUNITY TO DETERMINE WHETHER AEROBIC EXERCISE-INDUCED CHANGES TO HCC STATISTICALLY MEDIATES CHANGES TO COGNITION, AD NEUROPATHOLOGY, BRAIN VOLUME OR FUNCTION, AND IS IN LINE WITH THE NIH MISSION TO LEVERAGE EXISTING COHORT AND RCT SAMPLES FOR COST-EFFECTIVELY TESTING NEW HYPOTHESES. OUR PRIMARY AIMS INCLUDE: AIM 1. EXAMINE WHETHER EXERCISE-INDUCED CHANGES IN HCC STATISTICALLY MEDIATES COGNITIVE CHANGES RESULTING FROM THE INTERVENTION. AIM 2. EXAMINE WHETHER EXERCISE-INDUCED CHANGES IN HCC STATISTICALLY MEDIATES EXERCISE-RELATED CHANGES IN HIPPOCAMPAL AND PREFRONTAL FUNCTION AND VOLUME. AIM 3: EXAMINE WHETHER CHANGES IN HCC MEDIATES EXERCISE ASSOCIATIONS WITH AD NEUROPATHOLOGY. AIM 4: THE RESULTS FROM THE HCC ASSAYS OBTAINED FROM FUNDING THIS APPLICATION WILL BE INCORPORATED INTO THE LARGER IGNITE DATABASE AND WILL BE MADE AVAILABLE TO INVESTIGATORS INTERESTED IN EXPLORING HCC WITH THE RICH PHENOTYPING OF IGNITE PARTICIPANTS.
Obligated Amount:
487606.00
Face Value Of Loan:
0.00
Total Face Value Of Loan:
0.00
Date:
2024-04-01
Link:
View on USAspending
Awarding Agency Name:
Department of Health and Human Services
Transaction Description:
ADIPOGENESIS, TRIGLYCERIDE TURNOVER AND CELLULAR COMPOSITION OF ADIPOSE TISSUE IN RESPONSE TO ENDURANCE TRAINING (ATLAS) - PROJECT SUMMARY EXCESS ADIPOSITY – OBESITY – CAUSES INSULIN RESISTANCE (IR) IN WHITE ADIPOSE TISSUE (WAT) AND OTHER TISSUES. THE ROLE OF POOR WAT QUALITY IN IR, HOWEVER, IS LESS CLEAR. LOW ADIPOCYTE TRIGLYCERIDE (TG) TURNOVER, HIGH FORMATION RATES OF NEW ADIPOCYTES, HIGH SENESCENT CELL BURDEN, TISSUE AND CELLULAR INFLAMMATION AND HIGH CIRCULATING FREE FATTY ACIDS (FFAS) ALL CHARACTERIZE POOR WAT QUALITY. EXERCISE ENHANCES WHOLE-BODY IR AND DECREASES FASTING FFAS, INDEPENDENT OF REDUCTIONS IN FAT MASS, THUS HIGHLIGHTING THE SIGNIFICANCE OF EXERCISE EFFECTS ON WAT QUALITY. EVIDENCE OF THE DIRECT IMPACT OF EXERCISE – INDEPENDENT OF WEIGHT LOSS – ON IR WITHIN WAT IS LIMITED AND INCONCLUSIVE. THE UNDERLYING MECHANISMS THAT DRIVE EXERCISE-INDUCED CHANGES IN WAT BIOLOGY, SUCH AS NEW ADIPOCYTE FORMATION AND TG TURNOVER RATES, CELL COMPOSITION, SENESCENCE, AND INFLAMMATION, ARE POORLY UNDERSTOOD IN HUMANS. OURS WILL BE THE FIRST STUDY TO COMPREHENSIVELY ASSESS THE DIRECT EFFECTS OF EXERCISE ON WAT-SPECIFIC IR AND WAT QUALITY IN VIVO AND EX VIVO IN HUMANS. WE HAVE CONDUCTED GROUNDBREAKING STUDIES OF IN VIVO FORMATION OF NEW ADIPOCYTES AND ADIPOCYTE TG TURNOVER RATES USING A METABOLIC LABELING PROTOCOL THAT INCORPORATES DEUTERIUM (2H), ADMINISTERED AS 2H2O, INTO THE DNA AND TRIGLYCERIDES OF ADIPOSE CELLS. WE NOW HAVE COMPELLING PUBLISHED AND PRELIMINARY EVIDENCE THAT EXERCISE REDUCES IN VIVO FORMATION OF NEW ADIPOCYTES IN BOTH MICE AND HUMANS, SUGGESTING AN IMPORTANT EXERCISE-INDUCED MECHANISM OF WAT REMODELING. WE REASON THAT INCREASED ADIPOCYTE TG TURNOVER RATES IMPROVE ADIPOCYTE-SPECIFIC AND OVERALL WAT QUALITY AND THUS ABROGATE THE NEED FOR INCREASED FORMATION OF NEW ADIPOCYTES. USING OUR ESTABLISHED METHOD, WE WILL EMPLOY INNOVATIVE SINGLE NUCLEI TRANSCRIPTOMICS (SNRNASEQ) TO DISCOVER THE EFFECTS OF EXERCISE ON SENESCENCE AND INFLAMMATION WITHIN ADIPOCYTES AND NON-ADIPOCYTES OF WAT TO FURTHER UNDERSTAND HOW EXERCISE IMPACTS WAT QUALITY AND WAT- SPECIFIC IR VIA IN VIVO MICRODIALYSIS DURING INSULIN SUPPRESSION. IN THIS STUDY, WE WILL PERFORM A RANDOMIZED, CONTROLLED CLINICAL TRIAL TO EVALUATE THE IMPACT OF 12 WEEKS OF ENDURANCE EXERCISE ON ABDOMINAL SUBCUTANEOUS WAT ADIPOCYTE FORMATION AND TG TURNOVER IN VIVO, CELL COMPOSITION AND WAT-SPECIFIC LIPOLYTIC RATES UNDER PHYSIOLOGICAL INSULIN SUPPRESSION IN MEN AND PRE-MENOPAUSAL WOMEN WITH OBESITY. WE HYPOTHESIZE THAT ENDURANCE EXERCISE WILL INCREASE ADIPOCYTE TG TURNOVER RATES THEREBY DECREASING FORMATION OF NEW ADIPOCYTES, THE SIZE OF EXISTING ADIPOCYTES AND REDUCING INFLAMMATION AND SENESCENT CELL BURDEN IN ADIPOCYTES AND NON- ADIPOCYTES WITHIN WAT. THESE CELL-SPECIFIC CHANGES WILL PLAY A KEY ROLE IN EXERCISE-INDUCED IMPROVEMENTS IN WAT-SPECIFIC INSULIN-SUPPRESSED LIPOLYTIC RATES IN VIVO AND REDUCED FASTING FFA LEVELS. BY PERFORMING COMPREHENSIVE METABOLIC AND MOLECULAR PHENOTYPING OF WAT IN HUMANS IN RESPONSE TO EXERCISE, THESE PIVOTAL STUDIES WILL EXPAND OUR UNDERSTANDING OF WAT REMODELING AND HOW CHANGES IN THE CELLULAR COMPOSITION IMPACT THE OVERALL METABOLIC HEALTH OF THE ADIPOSE TISSUE IN THE CONTEXT OF OBESITY AND HELP IDENTIFY VIABLE TARGETS FOR INTERVENTIONS TO IMPROVE METABOLIC HEALTH.
Obligated Amount:
1413602.00
Face Value Of Loan:
0.00
Total Face Value Of Loan:
0.00
Date:
2024-01-09
Link:
View on USAspending
Awarding Agency Name:
Department of Health and Human Services
Transaction Description:
DETERMINING CELL- AND SPATIALLY-DISTINCT SKELETAL MUSCLE TRANSCRIPTIONAL ABERRATIONS IN INSULIN RESISTANCE AND TYPE 2 DIABETES - PROJECT SUMMARY TYPE 2 DIABETES (T2D) IS ESTIMATED TO AFFECT 30 MILLION U.S. ADULTS AND SKELETAL MUSCLE (SKM) INSULIN RESISTANCE (IR) IS CONSIDERED TO BE ONE OF THE PRIMARY ABERRATIONS. EFFECTIVE INSULIN-STIMULATED SKM GLUCOSE UPTAKE IS DEPENDENT ON 1) INSULIN-STIMULATED ACTIVATION OF TERMINAL ARTERIOLE ENDOTHELIAL CELLS (EC) TO PERFUSE MICROVASCULAR UNITS, 2) TRANSPORT OF SUBSTRATES ACROSS CAPILLARY ECS AND 3) STIMULATION OF MYOFIBER INSULIN SIGNALING, RESULTING IN GLUCOSE UPTAKE. THEREFORE, BOTH MYOFIBERS AND ECS ARE CRITICAL CELL TYPES THAT CAN BE DYSREGULATED WITH IR IN T2D. PREVIOUS RESEARCH HAS IDENTIFIED A DYSREGULATED TRANSCRIPTIONAL PROFILE WITH SKM IR IN THE BASAL STATE AND DURING INSULIN STIMULATION FROM A HYPERINSULINEMIC EUGLYCEMIC CLAMP (HE). A SIGNIFICANT LIMITATION OF THESE PRIOR STUDIES IS THE RESTRICTION TO WHOLE SKM HOMOGENATES AND THEREFORE NOT IDENTIFYING WHICH CELLS OR SPATIAL AREA THE DYSREGULATED SIGNALS ORIGINATE FROM. WE HAVE DEVELOPED A PIPELINE FOR 3’ AND 5’ AMPLIFICATION OF SINGLE CELLS OR NUCLEI FROM SKM USING FULL-LENGTH SMART-SEQ TECHNOLOGY WITH THE ICELL8 PLATFORM, RESULTING IN 2-3 FOLD GREATER GENE COVERAGE THAN PREVIOUS RESEARCH, ALLOWING US TO INVESTIGATE TRANSCRIPTIONAL ABERRATIONS AT A SINGLE CELL/NUCLEI RESOLUTION. RECENT DEVELOPMENTS IN SPATIAL TRANSCRIPTOMICS NOW PERMIT TRANSCRIPTIONAL PROFILING ON SECTIONED TISSUE. IN THIS PROPOSED RESEARCH, WE WILL LEVERAGE BOTH FULL-LENGTH SINGLE CELL AND SINGLE NUCLEI RNA-SEQ AND SPATIAL TRANSCRIPTOMICS TO DETERMINE CELL- AND SPATIALLY-DISTINCT TRANSCRIPTIONAL ABERRATIONS IN SKM THAT OCCUR WITH IR IN T2D. THE CAREER DEVELOPMENT TRAINING WILL REFINE MY SKILLS IN; LEADING AN INDEPENDENT LAB, BIOINFORMATICS, AND HUMAN CLINICAL RESEARCH WITH A FOCUS ON ASSESSING INSULIN-STIMULATED GLUCOSE DISPOSAL (RD) AND NON- OXIDATIVE GLUCOSE DISPOSAL (NOGD) USING HYPERINSULINEMIC EUGLYCEMIC (HE) CLAMPS WITH GLUCOSE TRACERS AND INDIRECT CALORIMETRY. MY K99/R00 TRAINING WILL UNIQUELY POSITION ME TO CONDUCT BEDSIDE-TO-BENCH-TO-BIOINFORMATICS RESEARCH TO UNCOVER THE MOLECULAR PROFILES OF SKM IR. FOR THE FIRST TIME, THE TRANSCRIPTIONAL RESPONSES TO INSULIN IN HUMAN SKM WILL BE PROBED AT A SINGLE CELL/NUCLEI AND SPATIAL RESOLUTION. WE WILL IDENTIFY WHICH CELLS AND AREAS OF SKM RESPOND TO INSULIN AND IF THEY ARE SPATIALLY LOCALIZED TO EACH OTHER AND IF THEIR GENE-NETWORK PROFILES CORRELATE WITH A GREATER IN VIVO RD AND NOGD ASSESSED SIMULTANEOUSLY WITH A HE CLAMP. THIS NOVEL AND INNOVATIVE APPROACH WILL REVEAL WHICH CELLS (AND IMPORTANTLY, WHERE IN SKM) THE ABERRATIONS OCCUR WITH IR IN T2D. THE TRANSLATIONAL RESEARCH INSTITUTE AT ADVENTHEALTH IS AN IDEAL ENVIRONMENT FOR DEVELOPING MY BEDSIDE-TO- BENCH-TO-BIOINFORMATICS RESEARCH APPROACH WITH CUTTING-EDGE METABOLIC TRANSLATIONAL RESEARCH FACILITIES AND A RICH INTERDISCIPLINARY ENVIRONMENT. COMPLETION OF THE PROPOSED RESEARCH AND CAREER DEVELOPMENT TRAINING WILL FACILITATE MY SUCCESS AS AN INDEPENDENT TRANSLATIONAL INVESTIGATOR IN SKM METABOLISM AND IR. FURTHERMORE, EXPERIMENTS IN THIS PROPOSAL WILL IDENTIFY SPECIFIC MOLECULAR TARGETS TO ALLEVIATE SKM IR THAT WILL BE TARGETED IN FUTURE GRANT APPLICATIONS.
Obligated Amount:
181500.00
Face Value Of Loan:
0.00
Total Face Value Of Loan:
0.00
Date:
2023-09-22
Link:
View on USAspending
Awarding Agency Name:
Department of Health and Human Services
Transaction Description:
COMMUNITY PROJECT FUNDING/CONGRESSIONALLY DIRECTED SPENDING - CONSTRUCTION
Obligated Amount:
1000000.00
Face Value Of Loan:
0.00
Total Face Value Of Loan:
0.00

OSHA's Inspections within Industry

Inspection Summary

Date:
2024-05-22
Type:
Planned
Address:
2135 SPRINT BOULEVARD, APOPKA, FL, 32703
Safety Health:
Safety
Scope:
NoInspection

Inspection Summary

Date:
2023-11-03
Type:
Planned
Address:
2135 SPRINT BOULEVARD, APOPKA, FL, 32703
Safety Health:
Safety
Scope:
Partial

Inspection Summary

Date:
2022-06-02
Type:
Monitoring
Address:
601 E ROLLINS ST SUITE 400, ORLANDO, FL 32803, ORLANDO, FL, 32803
Safety Health:
Health
Scope:
Partial

Inspection Summary

Date:
2020-09-08
Type:
Referral
Address:
601 E. ROLLINS STREET, ORLANDO, FL, 32803
Safety Health:
Safety
Scope:
Partial

Inspection Summary

Date:
2020-07-14
Type:
Fat/Cat
Address:
2600 WESTHALL LN., 2ND FLOOR, MAITLAND, FL, 32751
Safety Health:
Health
Scope:
Complete

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BROMME JEFF

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900 HOPE WAY, ALTAMONTE SPRINGS, FL, 32714

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900 HOPE WAY, ALTAMONTE SPRINGS, FL, 32714

CARE FOR THE CARE GIVER, L.L.C. AHS ACQUISITION II CORPORATION MISSION STRATEGIES, INC. AHS ACQUISITION III CORPORATION AHS ACQUISITION IV CORPORATION REAL PROPERTY HOLDINGS OF ADVENTIST CARE CENTERS, LLC AHS ACQUISITION CORPORATION QUALITY CIRCLE FOR HEALTHCARE, INC. CENTRAL TEXAS MEDICAL CENTER, INC. AHS RESOURCE PERSONNEL, INC.

Date of last update: 03 Jun 2025

Sources: Florida Department of State

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